Elizabeth Holmes dropped out of Stanford at 19 to start the blood-testing startup Theranos.
Theranos' value grew to $9 billion until flaws in the technology were exposed and Holmes was charged with fraud.
Here's how Holmes went from precocious child, to ambitious Stanford dropout, to an embattled startup founder now in prison.
Elizabeth Holmes was born on February 3, 1984 in Washington, DC. Her mom, Noel, was a Congressional committee staffer, and her dad, Christian Holmes, worked for Enron before moving to government agencies like USAID.
When she was 7, Holmes tried to invent her own time machine, filling up an entire notebook with detailed engineering drawings. At the age of 9, Holmes told relatives she wanted to be a billionaire when she grew up. Her relatives described her as saying it with the "utmost seriousness and determination."
Holmes had an "intense competitive streak" from a young age. She often played Monopoly with her younger brother and cousin, and she would insist on playing until the end, collecting the houses and hotels until she won. If Holmes was losing, she would often storm off. More than once, she ran directly through a screen on the door.
Elizabeth Holmes, CEO of Theranos, attends a panel discussion during the Clinton Global Initiative's annual meeting in New York, September 29, 2015.
It was during high school that Holmes developed her work ethic, often staying up late to study. She quickly became a straight-A student, and even started her own business: she sold C++ compilers, a type of software that translates computer code, to Chinese schools.
Holmes started taking Mandarin lessons and part-way through high school, talked her way into being accepted by Stanford University’s summer program, which culminated in a trip to Beijing.
Inspired by her great-great-grandfather Christian Holmes, a surgeon, Holmes decided she wanted to go into medicine. But she discovered early on that she was terrified of needles. Later, she said this influenced her to start Theranos.
Holmes went to Stanford to study chemical engineering. When she was a freshman, she became a "president's scholar," an honor that came with a $3,000 stipend to go toward a research project.
STANFORD, CA - MAY 22: People ride bikes past Hoover Tower on the Stanford University campus on May 22, 2014 in Stanford, California. According to the Academic Ranking of World Universities by China's Shanghai Jiao Tong University, Stanford University ranked second behind Harvard University as the top universities in the world. UC Berkeley ranked third. (Photo by Justin Sullivan/Getty Images)
As a sophomore, Holmes went to one of her professors, Channing Robertson, and said: "Let's start a company." With his blessing, she founded Real-Time Cures, later changing the company's name to Theranos. Thanks to a typo, early employees’ paychecks actually said "Real-Time Curses."
Holmes soon filed a patent application for a "medical device for analyte monitoring and drug delivery," a wearable device that would administer medication, monitor patients' blood, and adjust the dosage as needed.
Theranos's business model was based around the idea that it could run blood tests, using proprietary technology that required only a finger pinprick and a small amount of blood. Holmes said the tests would be able to detect medical conditions like cancer and high cholesterol.
Theranos Chairman, CEO and Founder Elizabeth Holmes (L) and TechCrunch Writer and Moderator Jonathan Shieber speak onstage at TechCrunch Disrupt at Pier 48 on September 8, 2014 in San Francisco, California
Holmes started raising money for Theranos from prominent investors like Oracle founder Larry Ellison and Tim Draper, the father of a childhood friend and the founder of prominent VC firm Draper Fisher Jurvetson. Theranos raised more than $700 million, and Draper has continued to defend Holmes.
Holmes took investors' money on the condition that she wouldn't have to reveal how Theranos' technology worked. Plus, she would have the final say over everything having to do with the company.
That obsession with secrecy extended to every aspect of Theranos. For the first decade Holmes spent building her company, Theranos operated in stealth mode. She even took three former Theranos employees to court, claiming they had misused Theranos trade secrets.
Holmes' attitude toward secrecy and running a company was borrowed from a Silicon Valley hero of hers: former Apple CEO Steve Jobs. Holmes started dressing in black turtlenecks like Jobs, decorated her office with his favorite furniture, and like Jobs, never took vacations.
Even Holmes's uncharacteristically deep voice may have been part of a carefully crafted image intended to help her fit in in the male-dominated business world. In ABC's podcast on Holmes called "The Dropout," former Theranos employees said the CEO sometimes "fell out of character," particularly after drinking, and would speak in a higher voice.
Former U.S. President Bill Clinton and Elizabeth Holmes, CEO of Theranos, during the Clinton Global Initiative's annual meeting in New York.
Holmes was a demanding boss and wanted her employees to work as hard as she did. She had her assistants track when employees arrived and left each day. To encourage people to work longer hours, she started having dinner catered to the office around 8 p.m. each night.
More behind-the-scenes footage of what life was like at Theranos was revealed in leaked videos obtained by the team behind the HBO documentary "The Inventor: Out for Blood in Silicon Valley." The more than 100 hours of footage showed Holmes walking around the office, scenes from company parties, speeches from Holmes and Balwani, and Holmes dancing to "U Can't Touch This" by MC Hammer.
Theranos founder Elizabeth Holmes at the company's headquarters.
Shortly after Holmes dropped out of Stanford at age 19, she began dating Theranos president and COO Sunny Balwani, who was 20 years her senior. The two met during Holmes' third year in Stanford’s summer Mandarin program, the summer before she went to college. She was bullied by some of the other students, and Balwani had come to her aid.
Balwani became Holmes' No. 2 at Theranos despite having little experience. He was said to be a bully and often tracked his employees' whereabouts. Holmes and Balwani eventually broke up in spring 2016 when Holmes pushed him out of the company.
In 2008, the Theranos board decided to remove Holmes as CEO in favor of someone more experienced. But over the course of a two-hour meeting, Holmes convinced them to let her stay in charge of her company.
As Theranos started to rake in millions of funding, Holmes became the subject of media attention and acclaim in the tech world. She graced the covers of Fortune and Forbes, gave a TED Talk, and spoke on panels with Bill Clinton and Alibaba's Jack Ma.
Elizabeth Holmes with former President Bill Clinton, left, and Alibaba cofounder Jack Ma.
Theranos quickly began securing outside partnerships. Capital Blue Cross and Cleveland Clinic signed on to offer Theranos tests to their patients, and Walgreens made a deal to open Theranos testing centers in their stores. Theranos also formed a secret partnership with Safeway worth $350 million.
In 2011, Holmes hired her younger brother, Christian, to work at Theranos, although he didn’t have a medical or science background. Christian Holmes spent his early days at Theranos reading about sports online and recruiting his Duke University fraternity brothers to join the company. People dubbed Holmes and his crew the "Frat Pack" and "Therabros."
Holmes was obsessed with security at Theranos. She asked anyone who visited the company’s headquarters to sign non-disclosure agreements before being allowed in the building and had security guards escort visitors everywhere — even to the bathroom.
Michael Dalder/Reuters
Holmes hired bodyguards to drive her around in a black Audi sedan. Her nickname was "Eagle One." The windows in her office had bulletproof glass.
Around the same time, questions were being raised about Theranos' technology. Ian Gibbons — chief scientist at Theranos and one of the company's first hires — warned Holmes that the tests weren't ready for the public to take and that there were inaccuracies in the technology. Outside scientists began voicing their concerns about Theranos, too.
By August 2015, the FDA began investigating Theranos, and regulators from the government body that oversees laboratories found "major inaccuracies" in the testing Theranos was doing on patients.
By October 2015, Wall Street Journal reporter John Carreyrou published his investigation into Theranos's struggles with its technology. Carreyrou's reporting sparked the beginning of the company's downward spiral.
Carreyrou found that Theranos' blood-testing machine, named Edison, couldn't give accurate results, so Theranos was running its samples through the same machines used by traditional blood-testing companies.
Holmes appeared on CNBC's "Mad Money" shortly after the WSJ published its story to defend herself and Theranos. "This is what happens when you work to change things, and first they think you're crazy, then they fight you, and then all of a sudden you change the world," Holmes said.
In July 2016, Holmes was banned from the lab-testing industry for two years. By October, Theranos had shut down its lab operations and wellness centers.
In March 2018, Theranos, Holmes, and Balwani were charged with "massive fraud" by the SEC. Holmes agreed to give up financial and voting control of the company, pay a $500,000 fine, and return 18.9 million shares of Theranos stock. She also isn't allowed to be the director or officer of a publicly traded company for 10 years.
Despite the charges, Holmes was allowed to stay on as CEO of Theranos, since it's a private company. The company had been hanging on by a thread, and Holmes wrote to investors asking for more money to save Theranos. "In light of where we are, this is no easy ask," Holmes wrote.
In Theranos' final days, Holmes reportedly got a Siberian husky puppy named Balto that she brought into the office. However, the dog wasn't potty trained, and would go to the bathroom inside the company's office and during meetings.
In June 2018, Theranos announced that Holmes was stepping down as CEO. On the same day, the Department of Justice announced that a federal grand jury had charged Holmes, along with Balwani, with nine counts of wire fraud and two counts of conspiracy to commit wire fraud.
Elizabeth Holmes, founder and CEO of Theranos, speaks at the Wall Street Journal Digital Live (WSJDLive) conference at the Montage hotel in Laguna Beach, California, October 21, 2015.
Theranos sent an email to shareholders in September 2018 announcing that the company was shutting down. Theranos reportedly said it planned to spend the next few months repaying creditors with its remaining resources.
Around the time Theranos' time was coming to an end, Holmes made her first public appearance alongside William "Billy" Evans, a 27-year-old heir to a hospitality property management company in California. The two reportedly first met in 2017, and were seen together in 2018 at Burning Man, the art festival in the Nevada desert.
Holmes is said to wear Evans' MIT "signet ring" on a chain around her neck, and the couple reportedly posts photos "professing their love for each other" on a private Instagram account. Evans' parents are reportedly "flabbergasted" at their son's decision to marry Holmes.
It's unclear where Holmes and Evans currently reside, but they were previously living in a $5,000-a-month apartment in San Francisco until April 2019. The apartment was located just a few blocks from one of the city's top tourist attractions, the famously crooked block of Lombard Street.
Lombard Place Apartments, where Holmes used to live.
It was later reported that Holmes and Evans got engaged in early 2019, then married in June in a secretive wedding ceremony. Former Theranos employees were reportedly not invited to the wedding, according to Vanity Fair.
Besides the criminal case, Holmes was also involved in a number of civil lawsuits, including one in Arizona brought by former Theranos patients over inaccurate blood tests. The lawyers representing her in the Arizona case said in late 2019 they hadn't been paid over a year and asked to be removed from Holmes' legal team.
Former Theranos CEO Elizabeth Holmes leaves after a hearing at a federal court.
Holmes' lawyers in the federal case had tried to get the government's entire case thrown out. In February 2020, Holmes caught a break after some of the charges against her were dropped when a judge ruled that some patients didn't suffer financial loss.
Amid the coronavirus outbreak, Holmes' lawyers asked the judge in April 2020 to deem the case "essential" so the defense team could defy lockdown orders and continue to travel and meet face-to-face. The judge said he was "taken aback" by the defense's pleas to violate lockdown.
It soon become clear that the pandemic — and the health risks associated with assembling a trial in one — would make the July trial date unrealistic. Through hearings held on Zoom, the presiding judge initially pushed the trial back to October 2020 and later postponed it further to March 2021.
Passengers wear masks as they walk through LAX airport.
In March 2021, Holmes requested another delay to the trial because she was pregnant. She asked to push back the trial to August 31, and her request was granted. Holmes reportedly gave birth to the child in July.
Nhat V. Meyer/MediaNews Group/Mercury News via Getty Images
The trial kicked off in September. In opening statements, prosecutors argued that, "Out of time and out of money, Elizabeth Holmes decided to lie." Meanwhile, the defense argued that although Theranos ultimately crumbled, "Failure is not a crime. Trying your hardest and coming up short is not a crime."
Theranos founder Elizabeth Holmes arrives at the Robert F. Peckham Federal Building with her defense team on August 31, 2021 in San Jose, California.
The list of possible witnesses for the trial named roughly 200 people, including the likes of Rupert Murdoch, Henry Kissinger, James Mattis, and Holmes herself.
Theranos founder Elizabeth Holmes leaves the Robert F. Peckham U.S. Courthouse with her mother, Noel Holmes, during her trial.
Over the course of 11 weeks, prosecutors called 29 witnesses to testify — including former Theranos employees, investors, patients, and doctors — before resting their case in November.
Holmes testified that Balwani controlled what she ate and how her schedule looked, told her she had to "become a new Elizabeth" to succeed in business, and forced her to have sex with him when she didn't want to because "he would say that he wanted me to know he still loved me."
Former Theranos COO Ramesh "Sunny' Balwani leaves the Robert F. Peckham U.S. Federal Court on June 28, 2019 in San Jose, California.
Holmes also admitted that she added some pharmaceutical companies' logos to Theranos' reports without authorization. Investors previously said they took some reassurance in those reports because, based on the logos, they thought major pharmaceutical companies had validated Theranos' technology. Holmes said she added the logos to convey that work was done in partnership with those companies, but in hindsight she wishes she had "done it differently."
Holmes also acknowledged on the stand that she hid Theranos' use of modified commercial devices from investors. She said she did this because company counsel told her that alterations the company made to the machines were trade secrets and needed to be protected as such.
In closing arguments, prosecutors argued that Holmes "chose fraud over business failure" while the defense argued she was "building a business, not a criminal enterprise."
Elizabeth Holmes walks into federal court in San Jose, Calif., Friday, Dec. 17, 2021.
After 15 weeks of trial, Holmes' case headed to a jury of eight men and four women on December 17, 2021.
Elizabeth Holmes, founder and former CEO of blood testing and life sciences company Theranos, leaves the courthouse with her husband Billy Evans after the first day of her fraud trial in San Jose, California on September 8, 2021.
Jurors deliberated for a total of seven days over the next few weeks before telling the court on January 3, 2022, that they were deadlocked on three of the 11 charges against Holmes. The judge read off some jury instructions to the group in court before instructing them to go back and deliberate further.
Hours later, the jury returned a mixed verdict for Holmes, finding her guilty on one count of conspiracy to defraud investors and three counts of wire fraud. They found her not guilty on four other counts and failed to reach a verdict on the remaining three counts.
The counts Holmes was found guilty of were all related to investments; she wasn't convicted on any of the charges involving patients who received inaccurate test results.
Holmes faced the possibility of decades in prison. Each count carries a maximum 20-year prison sentence, a $250,000 fine, and a requirement to pay victims restitution.
Holmes is played by Amanda Seyfried in the dramatized series, which asks the question, "How did the world's youngest self-made female billionaire lose it all in the blink of an eye?"
In a 24-page filing on May 27, Holmes' attorneys argued for her acquittal, saying the evidence was "insufficient to sustain the convictions."
Nick Otto/AFP via Getty Images
They wrote, "Because no rational juror could have found the elements of wire fraud and conspiracy to commit wire fraud beyond a reasonable doubt on this record, the Court should grant Ms. Holmes' motion for judgment of acquittal."
"Even if Ms. Holmes committed wire fraud against an investor (she did not) and even if Mr. Balwani committed wire fraud against an investor, that does not prove a conspiratorial agreement between them, nor does it prove that Ms. Holmes willfully joined any agreement," the attorneys continued in the filing.
But that wasn't the end: Holmes filed three motions requesting a new trial, one of which centered on the testimony of a prosecution witness who allegedly went to Holmes' house in August and expressed regret that he helped convict her.
The witness was former Theranos lab director Adam Rosendorff. According to an account of the incident from Billy Evans, Holmes' partner, Rosendorff showed up at their home looking "disheveled" and said he felt "guilty."
David Odisho/Getty Images
"He said when he was called as a witness he tried to answer the questions honestly but that the prosecutors tried to make everybody look bad (in the company)," Evans recalled in an email to Holmes' attorneys about their interaction. "He said that the government made things sound worse than they were when he was up on the stand during his testimony. He said he felt like he had done something wrong. And that this was weighing on him, He said he was having trouble sleeping."
In another of Holmes' motions for a new trial, she says the prosecution portrayed her relationship with Balwani differently in their respective trials, to her detriment.
In the final motion, Holmes said she was denied emails showing prosecutors failed to take appropriate steps to preserve a Theranos database that she claims would have helped her defense, even though the government furnished these materials when Balwani was on trial.
Holmes notched a small victory when the presiding judge ordered an evidentiary hearing regarding Rosendorff's testimony and appearance at her home. This hearing meant that Holmes' sentencing was postponed from October 17, 2022, to November 18 of that year.
Dai Sugano/MediaNews Group/The Mercury News via Getty Images
The evidentiary hearing proved useless to Holmes, though, as witness Rosendorff said he stood by his initial testimony and only went to her home because he was "distressed" at the idea of Holmes' child growing up without a mother.
Justin Sullivan/Getty Images
"At all times the government encouraged me to tell the truth and only the truth," Rosendorff clarified at the hearing.
"I don't want to help Ms. Holmes," Rosendorff added. "The only person that can help her is herself. She needs to pay her debt to society."
On November 8, the presiding judge denied all three of Holmes' motions for a new trial, paving the way for sentencing.
Chris Ryan/Getty
Days before her sentencing, Holmes' attorneys asked that she get no more than 18 months, preferably under house arrest. They submitted 130 letters from friends and family — spanning everyone from Senator Cory Booker to even an ex-CDC chief — pleading for leniency.
In the end, Holmes' friends and family didn't get their wish. On November 18, 2022, Holmes was sentenced to 135 months, or 11.25 years, in prison with three years of supervised release beginning on April 27. "I stand before you taking responsibility for Theranos. I loved Theranos, it was my life's work," Holmes said through tears at the hearing.
Meanwhile, Balwani's trial began in March 2022 and also returned a conviction. He was found guilty in July on all 12 counts brought against him, and in early December Balwani was sentenced to nearly 13 years in prison with three years of probation. As with Holmes, restitution will be decided at a later date. The judge ordered Balwani to self-surrender on March 15, 2023.
Former Theranos COO Ramesh "Sunny" Balwani and his legal team leave the Robert F. Peckham Federal Building on July 7, 2022 in San Jose, California.
Holmes appealed her conviction in December 2022, and US prosecutors said in recent court filings that she "continues to show no remorse to her victims" and is currently living on an estate that costs $13,000 a month.
In February 2023, a court filing revealed Holmes recently gave birth to a second child. She also asked the judge to delay the start of her prison sentence to allow her to remain free while she appeals her conviction.
Holmes in a federal court in San Jose, California, on November 18, 2022.
Nic Coury/AP
"Ms. Holmes has deep ties to the community: She is the mother of two very young children; she has close relationships with family and friends, many of who submitted letters at sentencing vouching for her good character; and she volunteers with a rape crisis and counseling organization," the filing said.
But Holmes appealed the judge's decision. In accordance with court rules, since she was on bail when she filed the motion, her prison reporting date was automatically delayed.
Philip Pacheco/Getty Images
Balwani previously used the same tactic and was able to push back his initially scheduled prison reporting date by a month — but still ultimately reported to prison on April 20.
In a May 7 profile in The New York Times, Holmes portrayed herself as a doting mother of two who wears a "bucket hat and sunglasses" and walks about the San Diego Zoo. She also wants to be called "Liz" as this is the "real Elizabeth."
She said that with her partner Evans, she spent six months in 2019 traveling the country in an RV and sleeping in campgrounds and Walmart parking lots.
Holmes admitted in her interviews with The Times that she had built a persona that wasn't "authentic" – wearing black turtlenecks, red lipstick, messy blonde hair, and using an exaggerated masculine voice.
In May, Holmes was again denied her request to remain free while she appeals her conviction, and a judge ordered her to report to prison May 30. She and Balwani were also ordered to pay $452 million in restitution to victims of Theranos' fraud.
On May 30, Holmes reported to Federal Prison Camp in Bryan, Texas, a minimum-security women's prison about 100 miles from Houston, where she grew up, to begin serving her sentence.
Elizabeth Holmes arrives at the Federal Prison Camp in Bryan, Texas, on May 30, 2023.
In the time since she's been incarcerated, her prison term has been shortened. Previously, Holmes had her sentenced shortened to roughly 9.5 years compared to her original 11.25-year sentence.
Disgraced Theranos CEO Elizabeth Holmes, left, is escorted by prison officials into a federal women’s prison camp on Tuesday, May 30, 2023, in Bryan, Texas.
Michael Wyke/Associated Press
The Bureau of Prisons did not immediately respond to Insider's request for comment on how Holmes' release date was calculated.
Release date calculations typically take into account factors like a person's surrender date, jail-time credit, the completion of substance abuse programs, and good behavior.
Maya Kosoff, Paige Leskin, and Áine Cain contributed to earlier versions of this story.
Holmes's sentence is reduced again. In May 2024, Bureau of Prisons records showed that Holmes' release date is now scheduled for August 16, 2032.
Elizabeth Holmes.
Justin Sullivan/Getty Images
Prison officials previously moved Holmes's release date to December 29, 2032. Shortening her sentenced by an additional three months brings Holmes' original sentence down by about two full years.
Holmes is still serving her time in Federal Prison Camp Bryan in Texas. Holmes's appeal is scheduled to go before a federal appeals court on June 11.
Elizabeth Holmes hugging her father, Christian Holmes IV as her mother, Noel Holmes, looks on.
Philip Pacheco/Getty Images
In May 2023, a court denied Holmes' motion to remain free on bail while she appealed her trial, remanding her to Federal Prison Camp Bryan in Texas, a minimum security women's prison. Federal appeals courts in San Francisco will hear opening arguments in her appeal and that of her co-defendant, Sunny Balwani, on June 11.
