The eureka moment that drove Oprah to reframe weight loss and banish shame involved a Post-It

Tech Insider : Business, Environment
oprah at gala
Oprah Winfrey at the American Ballet Theatre Gala on October 22, 2025.

Lanna Apisukh/WWD via Getty Images

Oprah has endured as a weight-loss icon. Not even GLP-1s can change that.

Tech Insider : Business
Oprah Winfrey on stage in a white dress with a microphone, holding her hand out to the audience.
Oprah Winfrey has massively influenced wellness and diet culture for decades, now taking the spotlight to share her experience with GLP-1s.

Don Arnold/Getty Images

Oprah Winfrey, 71, says she regrets not using GLP-1s sooner because of the 'wasted sadness and shame'

Tech Insider : Business
Oprah Winfrey
Oprah Winfrey

Theo Wargo/Getty Images

A cheaper, easier-to-use version of Wegovy is coming to the US soon

Tech Insider : Business
overweight person with a pill and water
Wegovy's new pill (not pictured) has been approved in the US, offering a needle-free option with a lower starting price than injections.

colnihko/Getty Images

Being hot is now a job requirement

Tech Insider : Business, Economy, Style
A woman applying lipstick is reflected in a laptop.

Getty Images; Rebecca Zisser/BI

Emily Reynolds runs a PR company, and with that responsibility comes the pressure to look young, she tells me.

Another perk of weight-loss drugs? Fewer colon cancer deaths, a study found

Tech Insider : Business, Environment
ozempic
Ozempic can cost anywhere from over $1,000 to a $25, depending on how you pay for it.

Peter Dazeley/Getty Images

Sam Altman says he tried semaglutide 'before it was cool' — and once ended up in a hospital

Tech Insider : Business, Technology
OpenAI CEO Sam Altman is pictured.
"Sometimes late at night, you just really want that chocolate chip cookie at 11:30," Sam Altman said.

Sebastian Gollnow/picture alliance via Getty Images

Why Omada Health is finally prescribing Ozempic as TrumpRx slashes GLP-1 weight-loss drug costs

Tech Insider : Business
Omada Health CEO Sean Duffy.
CEO Sean Duffy cofounded Omada Health in 2011.

Omada Health

Mark Cuban tips his hat to longtime foe Donald Trump for TrumpRx deal with Eli Lilly and Novo Nordisk

Tech Insider : Business
Donald Trump and Marc Cuban
President Donald Trump looks on during an event about pharmaceutical drugs in the Oval Office on November 6, 2025. Trump announced deals Thursday with pharmaceutical giants Eli Lilly and Novo Nordisk to lower the prices of some popular weight-loss drugs.

Andrew Harnik/Getty Images/ Tom Williams/CQ-Roll Call, Inc via Getty Images

The founder of a longevity startup said he follows 5 habits to curb brain aging after his dad was diagnosed with Alzheimer's

Tech Insider : Business
A portrait image of Dugal Bain-Kim, CEO of Lifeforce
Dugal Bain-Kim, CEO of Lifeforce

Courtesy of Dugal Bain Kim

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